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Sales continued to decline, and the stock price dropped by as much as 36%. What is Xpeng Motors’s ＂antidote＂？

The year 2024 has just begun, and Xpeng Motors is a bit "difficult".

In the delivery list in January, Xpeng Motors achieved a sales volume of 8,250 vehicles, down 59% month-on-month, which was the biggest drop among the new car-making forces. In February, sales in Xpeng Motors continued to decline, and only 4,545 new cars were delivered in February.

For the reason of the sales slump in February, He Xiaopeng attributed the reason to the production capacity of the new car X9. He said, "Due to too many orders, the production capacity has not kept up. In January, Tucki accumulated tens of thousands of orders for X9. At present, the difficulties faced by X9 have been solved, and the Spring Festival will fully work overtime to quickly improve the production capacity guarantee delivery."

In other words, the decline in sales is only temporary, and sales will gradually pick up in the future.

Although He Xiaopeng is still optimistic about the future of Xpeng Motors, the capital market does not see it this way. According to Kan Jian Finance, since 2024, Xpeng Motors’s share price has been falling continuously. As of the close of March 5, Xpeng Motors’s Hong Kong stock market closed at HK$ 35.95 per share. Although it has rebounded recently, its share price fell by as much as 36% in 2024.

Why did Xpeng Motors’s share price plummet by 36% in more than a month, and its performance was so bleak? In addition to the reason for the sharp drop in sales, what is the capital market still worried about?

Tucki’s "sleepy"

Xpeng Motors’s sales volume in January really fell far short of expectations.

According to official data, Tucki X9 delivered 2,478 vehicles in the first month, and the total sales of the remaining models were only 5,772 vehicles, including the main models-P7I and G6.

Of course, the production capacity of the new car X9 may have some problems, but the core of the problem at present is that even if the production capacity of the X9 can keep up, the sales volume in Xpeng Motors will not change much. After all, before the X9 was listed, the sales volume in Xpeng Motors could still exceed 10,000, but now after the new car is listed, the sales volume can’t even reach 10,000.

At present, it’s not easy for Xpeng Motors to increase sales again. After all, Xpeng Motors has been reducing prices and promoting sales since last December. According to media reports, Xpeng Motors has started several rounds of price cuts since December. For example, in early December, the maximum discount for all models of Tucki P7i was 26,000 yuan, and the maximum discount for Tucki G9, which was listed less than three months ago, was 19,000 yuan. In mid-December, Xpeng Motors announced that all G6 departments in Tucki would continue to reduce or exempt 10,000 yuan in a limited time. In January of this year, Xpeng Motors even announced that it would purchase the P7i Pengyi Performance Edition, and enjoy a limited-time subsidy of 50,000 yuan.

So many rounds of price cuts can’t move Xpeng Motors’s sales, which shows how much pressure Xpeng Motors is under now. This may also explain why Xpeng Motors’s share price performance has been so poor recently.

In fact, such a large-scale and continuous price reduction has brought many hidden dangers to Xpeng Motors’s performance. After all, Xpeng Motors is still at a loss.

According to the financial report, as of the third quarter of last year, the accumulated net profit of Xpeng Motors was-9.028 billion, the gross profit margin of the company as a whole was -2.7%, and the gross profit margin of the automobile business was -6.1%, which shows that Xpeng Motors is still in a situation of "selling one car and losing another". According to the recent price reduction, Xpeng Motors’s losses will further expand in the fourth quarter.

However, in order to stabilize sales, Xpeng Motors has neglected so much. According to media reports, since February, Xpeng Motors has launched a new round of price reduction promotion.

According to media reports, from February 1, 2024 to February 29, 2024, the 2024 Tucki G9 will receive a maximum of 10,000 yuan in cash during the Spring Festival, and a maximum of 11,000 yuan in limited-time optional discount, starting from 253,900 yuan for the whole department. At present, the official normal guide price of the 2024 Tucki G9 is 263,900-359,900 yuan.

However, the "drug effect" of price reduction tends to be smaller and smaller, and it can be predicted that the price reduction of ——G9 will have very limited sales promotion effect in Xpeng Motors.

How does Tucki "break through"?

For Xpeng Motors, the decline in sales is not the biggest problem. What is more serious is that its moat is becoming more and more fragile.

Previously, Kan Jian Finance had repeatedly analyzed Xpeng Motors, a car company. Among the three new forces, Xpeng Motors has the strongest scientific and technological attribute, and Xpeng Motors also wants to build its own scientific and technological moat. According to the financial report, in the past five years, Xpeng Motors’s R&D expenditure was about 15 billion, and it was this huge R&D expenditure that led to its losses year after year.

About two years ago, when the new energy vehicle market was still in the state of automation transformation, Xpeng Motors succeeded in creating scientific and technological attributes by virtue of its first-Mover advantage. However, with the competition of new energy vehicles entering the second half, more and more car companies are now making intelligent transformation, and the advantages of Xpeng Motors are becoming less and less obvious, especially with Huawei’s massive entry into the new energy vehicle market.

As far as the most important intelligent driving technology is concerned, Huawei has a tendency to surpass Tucki from three aspects: algorithm, computing power and data.

In terms of algorithm, Xpeng Motors chose NVIDIA Drive series chips and developed operators in software development, but Huawei is a self-developed chip, and only Huawei in China has realized mass production using network algorithms; In terms of computing power, Huawei’s current computing power on autopilot training is 1800P, which is three times that of Xpeng Motors’s 600P. From the data point of view, it is in sharp contrast to the sharp drop in sales in Xpeng Motors-Huawei’s world, with better intelligent software and hardware, became the new force "sales champion" in January. Obviously, in the field of intelligence, the world of inquiry has replaced Xpeng Motors’s former position, and with the growth of Huawei, when more and more car companies begin to use Huawei’s technology, Xpeng Motors’s future will become more and more difficult.

Of course, for the road of intelligence, although more and more strong enemies have emerged, Xpeng Motors obviously does not intend to give up. During the launch conference of Xpeng Motors Spring Festival, He Xiaopeng set a new timetable for NGP intelligent assisted driving: in 2024, the "full range" and "point-to-point" XNGP will be promoted in China, including scenes such as paths, internal roads and parking lots; Promote worldwide research and development of XNGP this year and next-research and development of high-speed NGP worldwide in 2024 and XNGP worldwide in 2025, which shows that Xpeng Motors will continue to invest in research and development in the future.

At present, in the face of increasingly fierce competition in the new energy vehicle market, there is not much Xpeng Motors can do but insist. But can Xpeng Motors really "survive" in the face of Huawei, a powerful competitor who has achieved good results in intelligence?

How about the cabbage price Chery Automobile and new energy coming to Jietu Shanhai T2？

There are many bright spots. Today, let’s talk about how it performs in terms of power. Next, let’s see if its highlights can attract you with Xiaobian.

First of all, from the appearance, the front face of Jietu Shanhai T2 looks rounder and looks very stocky. Headlights are very in line with consumers’ aesthetics, adding a sense of exquisiteness. The car is equipped with LED daytime running lights, front fog lights, automatic opening and closing, adaptive far and near light, delayed closing and so on. Coming to the side of the car body, the size of the car body is 4785 mm * 2006 mm * 1875 mm. The car adopts fashionable and dynamic lines, and the side gives people a very simple feeling. With large-sized thick-walled tires, the shape is eye-catching. In terms of the rear end, the rear end echoes the front face, the taillights are very fashionable and generous, and the overall shape is still very attractive.

Coming into the Jetway Shanhai T2 car, the front face of Jetway Shanhai T2 looks very cool and rich in functions. The steering wheel of the car is very in line with the interior style, made of leather, and its practicality and face value are not bad. Take a look at the central control. The car is equipped with a touch-sensitive LCD central control screen, which makes the interior design quite layered and conforms to the mainstream aesthetics. Finally, let’s look at the dashboard and seats. The dashboard design is remarkable and very eye-catching. The car adopts imitation leather seats, which are wide and thick, and have good support and comfort.

The space in the back row of Jetway Shanhai T2 is good, and it is no problem to meet the daily travel needs. At the same time, the car is equipped with fatigue warning, anti-lock braking (ABS), LED daytime running lights, brake assist (EBA/BAS, etc.), brake force distribution (EBD) main driver airbag, co-pilot airbag, side airbag curtain, front side airbag and other safety configurations.

The SUV has an atmospheric appearance, good spatial performance and high cost performance. I wonder if you are interested in it. I believe this car will definitely give you and your family a good experience.

Follow the Engineer to See Changan Auchan A800 Intelligent Control System

　　Speaking of the best-selling domestic seven-seat MPV, everyone will definitely think of Baojun 730. Yes, Baojun 730 can be said to be the benchmark model of this level. Now, Baojun 730 has received a challenge from Changan Auchan A800. This time Baojun 730 will be forced to take up the battle, and the theme of this war is the intelligent semantic recognition system. Today, we invited an engineer from Changan Auchan A800 to listen to him explain the advantages of this car to us.

　　First of all, from the appearance point of view, Changan Auchan A800 adopts the shell concept design language. Although it is a 7-seat MPV, its shape is not heavy, and the body lines are relatively coherent, which makes the whole body look clean and neat, showing a forward dive posture.

　　The performance of the interior is equally excellent, and the whole center console gives people the impression that the structure is regular and not sloppy, and at the same time it shows a certain level. From the point of view of face value, this car conforms to the aesthetics of young consumers.

　　Let’s follow the engineer’s perspective to see the most representative intelligent semantic recognition system on Auchan A800, which is also rare at the same level.

　　According to the engineer, this system is provided by Iflytek Company. There are two ways to wake up the semantic recognition system of Auchan A800, one is the multi-function key of the steering wheel, and the other is to wake up with the voice of "Hello Auchan" and "Hello Auchan". It is more convenient for the driver to use the buttons on the steering wheel, and the voice wake-up is convenient for the co-pilot or the rear passengers to operate.

　　In addition, this system can also change more than 10 local dialects and different types of voices, such as Northeast dialect, Cantonese, Sichuan dialect, etc., and can also set boys’ voices of different ages or sound quality. Enrich the fun of driving. This is also not available in the current mainstream voice system models.

　　When you choose the right voice category, you can interact with the computer. To operate navigation, just say the destination you want to go, and the computer will give corresponding feedback, and at the same time, you can recommend nearby restaurants, coffee shops and other peripheral facilities. At this time, you only need to say which item you want to choose by voice according to the prompts on the screen, and the system will help you switch to the destination you want to reach, so as to make navigation connection.

　　In addition to these, such as turning on and off the air conditioner, opening and closing the skylight, audio and other operational instructions, it can also be completed by speech recognition, similar to the Roewe RX5, a hot internet car. This Auchan A800 has all the necessary basic operations, and compared with Roewe RX5, this Auchan A800 is obviously superior in the intelligent semantic recognition system.

　　Since the Roewe RX5 was mentioned, the engineer told us a new function that RX5 didn’t have. For example, if you are bored while driving, and you happen to be a user who likes ancient poetry, you can have a discussion with our intelligent semantic recognition system. When you say so bright a gleam on the foot of my bed, the computer will quickly connect the latter sentence to interact with you, and when you say the last sentence, it can recite the whole article to you, which is very interesting.

　　Of course, the mathematical skill of this intelligent semantic recognition system is not bad. You can say all kinds of mathematical problems you can imagine to test it, which is sure to be faster than the speed of using a calculator.

　　When you are bored, you can also tell you jokes by talking to the intelligent semantic recognition system. According to the engineer, the jokes stored in it are enough for you to listen for a long time.

　　Or when you want to know the weather, tell the intelligent semantic recognition system where you want to know the weather, and it will help you collect the weather of the address on that day and in the next few days, which is very intimate.

　　The most incredible thing is that it can also purchase air tickets or train tickets by voice. As long as you say where you want to go on the date of the month, the system will quickly identify the air tickets of that day. After reading, you can directly say which one to choose to complete the operation, which is very convenient.

　　Summary of intelligent semantic recognition system;In fact, voice control has been carried on many models, and the intelligent semantic recognition system of Changan Auchan A800 is far more advanced than the voice control system used by most manufacturers at present. This semantic recognition system has nine kinds of voice control functions: communication, navigation, radio, music, track control, application, information service, body control and air conditioning, which can realize perfect man-machine interconnection.

　　Having said so much about the powerful functions of the intelligent semantic recognition system, the engineer also told me that the software that comes with this A800 is also very rich, such as the built-in Himalayan FM, which can listen to all kinds of radio programs through a large number of resources in the APP, thus realizing seamless connection with the mobile phone and enhancing the entertainment when driving.

　　In addition to voice and entertainment functions, the car can also be connected with Baidu CarLife to realize the interconnection of mobile phones, and the contents of mobile phones are synchronously mapped to the central big screen, so as to realize the synchronization operation. At this time, the songs that are often listened to in the mobile phone can be played in the car.

　　In the future, engineers also revealed that they will join the mobile phone wireless charger, and the output current can reach above 0.8A, which is basically the same as the mainstream car charger.

　　Finally, the engineer told me about the remote control function of the car with great interest. It is reported that this is an APP that only needs to bind the mobile phone through the frame number to realize remote control of the car. The remote control system relies entirely on the vehicle’s own 4G network. When we run the APP, it will automatically get the current state of the vehicle, remotely start the vehicle and control the air conditioning system in advance, which is definitely a super intimate configuration for the current summer.

　　Summary:Looking from the current models of this class, there is rarely a self-owned brand MPV with such a powerful intelligent semantic recognition system. The appearance of Changan Auchan A800 makes up for the shortcomings of self-owned brands in this respect, and once again changes the impression of self-owned MPV in the eyes of Chinese people. Back to the beginning of the article, although Baojun 730 is the best MPV at this price, I believe that with the listing of Changan Auchan A800 soon, Baojun 730′ s leading position will be lost, because this is an era of intelligent interconnection, an era of pursuing cost performance but pursuing quality life. The launch of Changan Auchan A800 is a cost-effective model that conforms to the times and the needs of users.

2024 Tank 300： Fashion Conqueror, with three models starting at RMB 199,800.

The popularity of tank 300 is a special phenomenon in the automobile market. The unwilling young people, relatively friendly price system and hard-core fashionable style have made this product series sell well. After some trimming, the 2024 tank 300 was put on sale, and the convenience and efficiency of use were improved.

The 2024 models include challenger, conqueror and passerby, and the suggested retail prices are 199,800 yuan, 216,800 yuan and 226,800 yuan respectively. Among them, the passer-by is a light-mixed vehicle with relatively excellent fuel economy.

2024 tank 300 Challenger and Conqueror upgraded the configuration, adding four-door windows with anti-pinch function and wireless fast charging function of 50W mobile phone. At the same time, equipped with snail horn and ETC.

The 2024 Tank 300 Crosser is upgraded based on the original city version, equipped with a 2.0T+9AT+48V light mixing system, with a maximum net power of 180kW and a maximum net torque of 380Nm. In terms of configuration, the passer-by also added four-door window one-button lifting, 50W mobile phone wireless fast charging, snail horn, ETC and other functions.

The 2024 Tank 300 continues to be equipped with a non-loaded body professional off-road chassis, with a approach angle of 33, a departure angle of 34 and a longitudinal passing angle of 23.1. Trailer hooks are equipped at the front and rear of the vehicle, and the safety holes are reserved and dragged. At the same time, the 2024 model is equipped with a new generation of ATS all-terrain control system, providing a variety of driving modes.

The 2024 Tank 300 is equipped with L2+ intelligent driving assistance system, which provides driving assistance functions such as ACC adaptive cruise and LKA lane keeping assistance. The 2024 model is also equipped with vehicle remote control function.

There is no need to blame the winners, and the hot sale of Tank 300 is also enlightening to many local enterprises. In the face of imitative competitors, tanks are also achieving self-improvement. Better fuel economy and richer standard configuration further enhance the market competitiveness of this series.

Huawei, big announcement! Yu Chengdong： epoch-making! Is the three-fold screen mobile phone coming？

On the morning of September 2, Huawei announced in Guanwei today that it will officially hold a new product launch conference on September 10.

Huawei announced that it will hold a new product launch conference on September 10th.

Huawei’s terminal said, "Extraordinary work, always highlights. At 14: 30 on September 10th, Huawei will see the Extraordinary Brand Festival and HarmonyOS Zhixing New Product Launch Conference, so stay tuned! " It is worth noting that Apple has just announced the time of the autumn new product launch conference: 1 am on September 10, Beijing time, with the theme of "highlight moment".

After Huawei’s official announcement, Yu Chengdong responded in Weibo that Huawei’s most leading, innovative and subversive products are coming!

"This is an epoch-making product that others thought but couldn’t do. After five years of persistence and investment, we turned science fiction into reality. Huawei’s peak work, so stay tuned! " Yu Chengdong said.

Yu Chengdong once revealed in the live broadcast of "Walking with Hui" that Huawei’s next-generation folding screen will be available soon after five years of research and development. "The next generation of folding screen, others can think of, but can’t do it. We have been thinking about it for five years, and finally it may be coming out soon. "

In August this year, several digital bloggers took photos of Huawei managing director Yu Chengdong operating a new machine in the engine room on social platforms. The photo shows that Yu Chengdong is holding a new three-fold screen.

It is reported that Huawei’s layout has been folded for many years, and it has applied for a number of patents related to folding screens as early as 2022. On February 21, 2024, Huawei applied for a patent called "folding screen device", which showed a new form of electronic device with three folds. The main structure includes three shells, two hinges and a flexible screen, and it uses an inner hinge and an outer hinge to connect the three shells. The agency said that in the second half of the year, Huawei will usher in the intensive release period of new products and further improve its layout in the middle-to-high end of the folding machine field.

Since the beginning of this year, the news that Huawei will launch a "three-fold screen mobile phone" has continued. Earlier, it was reported that Huawei had begun to stock up on three-fold screen mobile phones.

Huawei’s mobile phone sales regained the first place in China.

On August 29th, Huawei released its operating results for the first half of 2024. The overall operation was stable and the results were in line with expectations. In the first half of the year, Huawei achieved sales revenue of 417.5 billion RMB, a year-on-year increase of 34.3% and a net profit margin of 13.2%. According to this calculation, Huawei’s net profit in the first half of 2024 was 55.11 billion yuan, an increase of over 18% year-on-year, which exceeded the 50 billion mark for the first time.

In terms of mobile phone business, IDC data shows that in the first half of 2024, Huawei once again ranked first in the smartphone market in China with a market share of 17.5%, and the growth rate of mobile phone shipments in the first quarter and the second quarter was 110% and 50.2% respectively, leading the industry. Although external restrictions continue to tighten, Huawei’s supply capacity continues to improve, and the gap with Apple continues to narrow in the market above 4,000 yuan.

According to the open source securities research report, with the breakthrough of Huawei’s related technologies, the release of Mate 60, Pura 70 series and Mate X5 folding screen series will bring Huawei back to the domestic high-end mobile phone market. At present, Mate 60 and Pura 70 series are still hot, and domestic high-end machines have returned to the peak of sales.

In the second quarter of 2024, Huawei released the Pura 70 series, covering the price range from 5,499 yuan/set to 10,999 yuan/set. TechInsights said that in the second quarter, the proportion of Pura and Mate series in Huawei’s total shipments increased significantly year-on-year, which helped increase the average selling price of Huawei’s mobile phones.

According to the statistics of TechInsights, in the second quarter of 2024, the average wholesale selling price (ASP) and wholesale revenue of Huawei’s mobile phones both reached record highs, mainly due to the relatively large proportion of high-end models (Mate, Pura series and folding screen series). China market remains Huawei’s core market, accounting for 89% of its global smartphone shipments.

At the same time, the popularity of folding screen mobile phones has also helped Huawei’s average mobile phone revenue to reach a new high. The data shows that in the second quarter of 2024, Huawei’s sales of book Mate X series and flip Pocket series increased by 400% and 50% respectively.

Thanks to the popularity of mobile phones, the market share of HarmonyOS operating system in China increased to 17.2% in the first half of 2024, up 66.7% year-on-year, surpassing iOS and second only to Android. In June 2024, at Huawei Developers Conference 2024, Harmony OS NEXT (HarmonyOS Xinghe Edition) launched a Beta version for developers, which is also known as "Pure Blood HarmonyOS". It is based on the HarmonyOS kernel and is no longer compatible with the APP developed by Android. The top 5,000 mobile phone applications have all started the development of native applications in HarmonyOS.

Proofreading: Su Huanwen

26 measures! Ministry of Industry and Information Technology： Further Improving the Ability of Mobile Internet Application Services

　　Cctv newsIn order to optimize service supply, improve user experience, maintain a good information consumption environment, and promote the high-quality development of the industry, the Ministry of Industry and Information Technology recently issued a notice to deploy and further enhance the service capabilities of mobile Internet applications. Focusing on improving users’ service perception and industry management ability, that is, "two improvements", a total of 26 measures are put forward: First, focusing on APP installation and uninstallation, service experience, personal information protection, appeal response, etc., 12 measures are put forward to improve users’ service perception. Second, from the perspective of coordinated and standardized development of the industry and joint prevention and treatment of upstream and downstream, we should seize the five key subjects of current mobile Internet services, namely, APP development operators, distribution platforms, SDK (software development tools), terminals and access enterprises, and put forward 14 measures. The details are as follows:

Notice of the Ministry of Industry and Information Technology on Further Improving the Ability of Mobile Internet Application Services

　　In recent years, the Ministry of Industry and Information Technology has vigorously promoted the improvement of the quality of mobile Internet application services, effectively safeguarded the legitimate rights and interests of users, and achieved positive social results. However, some enterprises still have problems such as irregular service behaviors and inadequate implementation of related responsibilities. In order to optimize service supply, improve user experience, maintain a good information consumption environment, and promote the high-quality development of the industry, relevant matters are hereby notified as follows according to the Law on the Protection of Personal Information, Regulations on Telecommunications, Provisions on Regulating the Market Order of Internet Information Services, Regulations on the Protection of Personal Information of Telecommunications and Internet Users and other relevant laws and regulations:

　　First, enhance the service perception of the whole process and protect the legitimate rights and interests of users

　　(A) standardize the installation and unloading behavior

　　1. Ensure informed consent for installation.Recommend to users to download the APP should follow the principle of openness and transparency, clearly indicate the necessary information such as the development operator, product function, privacy policy, permission list, etc. in a true, accurate and complete manner, and provide obvious cancellation options at the same time, and download and install the app after the user confirms and agrees, so as to effectively protect the user’s right to know and choose. Do not cheat and mislead users to download and install by means of "stealing the beam and replacing the column", "forced binding" and "silent download".

　　2. Standardize the recommended downloading behavior of web pages.When users browse the content of the page, they are not allowed to download the APP automatically or forcibly without the user’s consent or active selection, or they are forced to download and open the APP by folding display, active pop-up, frequent prompts, etc., which affects the normal browsing of information by users. Without justifiable reasons, you may not bind downloading the APP to reading the content of the webpage.

　　3. Realize convenient unloading.In addition to the basic functional software, the APP should be easily uninstalled, and users should not be maliciously prevented from uninstalling by means of blank names, transparent icons, hidden background, etc.

　　(B) Optimize the service experience

　　4. Window closing is optional for users.The information window of screen opening and pop-up window provides a clear and effective close button to ensure that users can close it conveniently; Do not pop up the window frequently to interfere with the normal use of users, or use "full-screen heat map", high-sensitivity "shake" and other ways that are easy to cause false triggering to induce users to operate.

　　5. Inform the service matters in advance.Clearly express the product’s functional rights and interests, tariffs and other contents, and if there are additional conditions such as opening members and charging fees, it should be clearly indicated. Without express, it is not allowed to add restrictive conditions in the process of providing products and services, and use this as an excuse to terminate the normal use of product functions and services by users or reduce the service experience.

　　6. The startup and operation scenarios are reasonable.In the case of non-service necessity or unreasonable scenarios, it is not allowed to start and associate other apps, or to wake up, call or update.

　　7. Prompt reminder of service renewal.If the service is provided by automatic renewal or automatic renewal, the user’s consent shall be obtained, and it shall not be checked by default or forced to be bundled. Remind users by SMS and message push 5 days before automatic renewal and automatic renewal, and provide convenient ways to unsubscribe at any time and ways to cancel automatic renewal and automatic renewal during the service period.

　　(3) Strengthening the protection of personal information

　　8. Adhere to the principle of legality, justness and necessity.Personal information processing activities should have a clear and reasonable purpose, and users should not be forced to agree to personal information processing activities beyond the scope or unrelated to service scenarios just on the grounds of service experience, product development, algorithm recommendation and risk control. When a user refuses to provide personal information that is not necessary for the current service, it shall not affect the user’s use of the basic functions of the service.

　　9. Express personal information processing rules.Inform users of personal information processing rules in a concise, clear and easy-to-understand way, and inform users of the latest situation in time if there is any change. Highlight the purpose, method and scope of processing sensitive personal information, establish a list of collected personal information, and do not induce users to agree to the rules of personal information processing by default checking, narrowing text or lengthy text.

　　10. Reasonable application for permission.When the corresponding business function is started, dynamically apply for the required permissions, and the user shall not be required to agree to multiple necessary permissions that are not related to the business function. When calling the terminal photo album, address book, location and other rights, synchronously inform the user of the purpose of applying for the rights. Without the user’s consent, the user’s unauthorized permission status shall not be changed.

　　(D) Respond to user demands

　　11. Set up a customer service hotline.Encourage Internet companies to establish customer service hotlines, and major Internet companies will publicize the telephone numbers of customer service hotlines in prominent positions on websites and apps to simplify the manual service transfer procedures. Encourage the improvement of the response ability of customer service hotline, with the longest monthly response time of 30 seconds and the response rate of manual service exceeding 85%.

　　12. Properly handle user complaints.Publish effective contact information and accept user complaints. Respond to the complaints on the Internet information service complaint platform according to the requirements of the specification, ensure that they are handled within 15 days, and improve the satisfaction rate of complaint handling. Encourage the setting of user satisfaction evaluation links in the APP to guide users to participate in the evaluation.

　　Second, improve the whole chain management ability and create a healthy service ecology

　　(1) Implementing the main responsibility of APP development operators

　　1. Improve the internal management mechanism.Clarify the lead management department and person in charge of user service and rights protection, establish a life-cycle personal information protection mechanism, improve the assessment accountability system, implement relevant laws and regulations and policies in all aspects of product development, promotion and operation, and continuously improve the compliance level. Regularly conduct compliance audits on personal information protection measures and their implementation to effectively prevent potential risks.

　　2. Enhance technical support capabilities.Take security technical measures such as access control, technical encryption and de-identification to strengthen front-end and back-end security protection. Active monitoring found personal information disclosure, theft, tampering, damage, loss, illegal use and other risk threats, timely response to disposal requirements.

　　3. Strengthen software development tools (SDK) use management.Before using the SDK, evaluate its personal information protection ability, clearly stipulate the rights and obligations of all parties through contracts and other forms, and ensure that personal information processing is legal and compliant. Centralized display and timely update of the embedded SDK name, functions and rules for handling personal information. Dealing with users’ personal information together, which infringes on users’ rights and interests and causes damage, shall bear corresponding responsibilities according to law.

　　(2) Strengthen the platform distribution management.

　　4. Strictly review the APP.Accurately register and verify the basic information such as the true identity and contact information of the APP development operator, the main functions and uses of the APP, and conduct technical testing on the APP to be put on the shelves. The person in charge of the relevant audit shall be clearly defined, and the audit log records shall be kept, and those that do not meet the requirements shall not be put on the shelves. Publicize the APP on the shelf in full, and indicate the name and function of the APP, the development operator, the version number, the list of user terminal rights to be obtained and the use, personal information processing rules and other information in a prominent position. If the explicit interface for distribution has not been established, the APP download should be linked to the APP store to guide users to download the distributed app from formal channels.

　　5. strengthen the inspection of the APP on the shelf.Strengthen the dynamic inspection of APP to ensure that the publicity information is true and accurate. For illegal APPs that are inconsistent with the public information, or change the main functions of the app, the application authority, the scene and scope of personal information collection and use without authorization by means of "hot update or hot switch", the service should be stopped.

　　6. Improve the distribution management mechanism.Establish mechanisms such as credit evaluation and risk warning of APP development operators, encourage electronic signature authentication of distributed apps, and realize traceability of the whole process of application and distribution. Strengthen the linkage with the public service platform for detection and certification of mobile Internet applications, and do a good job in information reporting, monitoring and traceability, information sharing and response disposal.

　　(C) Standardize SDK application services

　　7. Establish an information publicity mechanism.Publicly express basic information such as SDK name, developer, version number, main functions, instructions for use, and personal information processing rules. If the SDK collects, transmits and stores personal information independently, it shall make a separate explanation. Encourage the role of SDK management service platform and guide APP development operators to use compliant SDK.

　　8. Optimize the function configuration.Follow the principle of minimum necessity, define the functions of SDK and the corresponding scope of personal information collection according to different APPlication scenarios or uses, and provide functional modules and configuration options for personal information collection to app developers and operators, and do not excessively collect personal information in a package.

　　9. Strengthen service coordination.In the whole life cycle of product use, actively provide compliance guidelines to APP developers and operators in a clear and easy-to-understand way, guide APP developers and operators to use them correctly and reasonably, and jointly improve the compliance level. When the personal information processing rules change or risks are found, update and inform the APP development operators in time.

　　(D) Build a terminal security line

　　10. strengthen APP operation management.Provide users with the closing function of self-startup and associated startup of the APP, as well as convenient options for resetting related device identification codes, strengthen the monitoring of silent download and hot update of the APP, and prevent unauthorized startup, download and installation without the user’s consent.

　　11. Strengthen the reminder of APP behavior record.Enhance the ability to record the behavior of permission calls, and provide convenience for users to query the situation of permission calls. Establish an obvious prompt mechanism for the status of permissions such as address book, microphone, camera, location and clipboard, so as to ensure users to know the status of personal information collection in time and accurately.

　　12. Improve the risk early warning capability of APP.Promote the development of APP electronic signature authentication, and provide early warning tips to users to improve the ability to identify counterfeit, bad, illegal and other risk apps.

　　(V) Consolidate the responsibility of access enterprises.

　　13. Accurate registration information.When providing network access services for APP and SDK, register and verify the real identity and contact information of the developers and operators of APP and SDK to improve traceability.

　　14. Ensure effective disposal.In accordance with the requirements of the telecommunications regulatory authorities, necessary measures such as stopping access to illegal apps and SDK shall be taken according to law to effectively prevent them from violating the rights and interests of users.

　　Third, the job requirements

　　(1) Do a good job in organization and implementation.All units should adhere to the people-centered development thought, improve their political stance, strengthen their responsibility, refine and decompose tasks, earnestly implement this notice, and ensure effective results. Relevant enterprises should implement the main responsibility, carry out self-examination and self-correction according to the requirements of this notice, and earnestly safeguard the legitimate rights and interests of users. At the same time, improve the long-term mechanism, innovate modes and methods, continuously improve the service level of mobile Internet applications, and continuously enhance users’ sense of acquisition, happiness and security.

　　(2) Strengthen guidance and supervision.The Ministry of Industry and Information Technology has improved the mechanism of evaluation, notification, ranking and publicity, promoted the work in a solid and orderly manner, and timely summarized and popularized excellent cases and experiences. Local communications administrations should strengthen supervision and inspection, guide and urge local enterprises to implement the requirements of this notice. If the implementation is not in place or there are violations, measures such as ordering rectification within a time limit, announcing to the public, and organizing the removal of the shelves shall be taken according to law, and serious accountability shall be investigated.

　　(3) Strengthen the application of technology.China Information and Communication Research Institute should organize industrial forces, comprehensively use new technologies and means such as artificial intelligence and big data, upgrade and build a national public service platform for testing and certification of mobile Internet applications, continuously improve platform functions, and do a good job in technical testing, monitoring services and supervision support. Actively promote the application of traceable technical means such as electronic signature authentication, and promote the improvement of service management capabilities.

　　(4) promoting industry self-discipline.Encourage industry associations and related institutions to formulate industry self-discipline conventions, technical standards and service specifications, and strengthen evaluation and certification and personnel training. Further unblock channels to listen to the opinions of the masses, promote exchanges and interactions between all parties, guide enterprises to operate in compliance with laws and regulations, continuously optimize and improve services, create a good environment for striving for Excellence and promoting mutual progress, and promote high-quality development with high-quality services.

Sedan experience／luxury configuration, test drive Lexus RX350

　　As the number one car company in Japan, the car has established an unshakable position in the global automotive field, but it has always been a little weak in the face of luxury brands such as Wo. So in 1987, Toyota re-established a high-end brand – Lexus. Later, for various reasons, this high-end brand was changed to its English literal translation -.

　　In today’s high-end market, models have become the "battleground" of various automakers. BMW X5, Benz ML-Class, VOLVO and other models have long been on the streets, and Lexus naturally does not miss the huge "cake" of SUVs. In order to face the continuous evolution of various competitors, Lexus also launched the more powerful RX350 on the basis of its original RX330. In 2006, the 350 became one of the best-selling luxury SUVs in the United States with 10,800 units.

● Unique shape

　　In terms of external dimensions, the RX350 is not the leading SUV model, with a length of 4740, a width of 1845, and a height of 1735 millimeters, respectively. However, compared with similar RVs, it is definitely large, and naturally lays a good foundation for its internal space.

The Lexus RX350 has a significant stylistic difference from its German competitors.

　　In terms of appearance, there is a huge stylistic difference between the Lexus RX350 and its German competitors. Compared with those German masterpieces, the RX series is more dynamic and spiritual, changing the clumsy image of traditional SUVs. The lines of the whole car are full and smart, and the body is sturdy, but not awkward. The inverted straight waterfall ghost face and sharp headlights are in line with the design style of Lexus this season. The fog lights are well integrated into the sturdy front bumper. The outward protruding wheel arches give the whole car a sense of strength. The rear of the car, which is oriented towards the slip-back design, also gives the RX more fashion sense. The sloping C-pillar and the rear triangular window combine perfectly to give the RX a very smooth side line. The translucent taillights outline the unique rear of the RX.

　　In addition to looking sporty, thanks to Toyota’s many years of wind tunnel testing, the RX350’s wind noise level is clearly controlled at a very low level due to the drag coefficient and aerodynamic performance of other competitors. The unique airflow-guided baseplate is derived from F1 racing technology. While reducing the impact of airflow on the body, the smooth baseplate accelerates the speed of airflow flowing away from the lower part of the body to counteract upper buoyancy and increase driving stability. In addition, the diversion system also directs two airstreams to the brakes to help the brakes dissipate heat.

● Warm and humane interior

　　The interior of the RX is a good example of Lexus’ ergonomic efforts. The light-colored main colors create a gentle overall style.

"Three round backlit meters feel full of technology"

　　For SUV models, there is naturally more attention to the front row. Located in the driver’s seat, various buttons are operated by hand. The three round backlit meters feel full of technology and exude a strong sporty atmosphere. The three-spoke steering wheel that echoes the meter feels comfortable, and the combination of leather and wood shows a luxurious atmosphere. The diameter and thickness of the wheel are very handy, and the audio-visual system and common buttons such as Bluetooth phones are integrated on it.

　　The seats with high line of sight support the human body in place, and the perforated leather seats fit the human body curve well. The front seats can be electrically adjusted in 8 directions, and they are all equipped with electric lumbar support, electric heating and armrests that can be retracted independently. Since there is no restriction on the C-pillar seat like an ordinary RV, the interior space of the RX350 can completely exceed that of a C-class RV. The rear seats can choose different lying angles, which will not reduce their legroom when choosing a larger lying angle. The rear occupants can lie down in the back row for a nap in great comfort.

● Exceptional power and transmission system

　　SUVs are not off-road vehicles, but a product of a relative balance between off-road vehicles and RVs. The reason why they are respected is because they have the good handling and comfort of RVs, as well as the passing capacity and carrying capacity that RVs cannot match. Coupled with the characteristics of good line of sight and strong safety, they are widely favored.

The RX350 is equipped with a V6 engine with a displacement of 3456 milliliters.

　　The RX350 is equipped with a 3456ml V6 engine, which is also a classic of Lexus and is used in many Lexus models. From the 94mm and 83mm strokes, it is not difficult to find that this engine is not designed for pure off-road, but the application of other technologies makes the engine have good output performance. In practical use, its torque performance is already excellent at more than 2500 rpm, and at 4700 rpm, it can burst out a maximum torque of 342 Nm. At 6200 rpm, it reaches a maximum of 203 kW.

Porsche’s new crossover is here, and it’s a man’s luxury car

In terms of appearance, the new Cayenne coupe is the same as the ordinary version. The biggest highlight is the back shape. The overall shape is very dynamic, and there is a very large spoiler at the rear, which is also a more imposing place than the ordinary version of the Cayenne model. And the distance between the door and the trunk cover of the new Cayenne coupe is very long, so it can also fully ensure the safety of the people in the car.

The interior workmanship of the 19 Cayenne is relatively fine; the configuration is relatively complete; the comfort of the seat is better; the configuration of the automatic heating of the steering wheel and the design of the armrest next to the seat is more user-friendly; the optional configuration such as panoramic sunroof and compass caters to the needs of some consumers to pursue individuality. The interior is luxurious beyond your imagination, and the space is more abundant; the interior workmanship is fine and the configuration is relatively rich; the control performance is good; the safety factor is high. The appearance of the imported version of the Cayenne has changed relatively little. The new Cayenne has less changes in appearance. The overall line is not much different from the old model. The front face of the new Cayenne is more obvious. The headlight group adopts a full LED light source and iq.light headlights, which illuminate a longer distance at night and have a longer

The length of the car is 4932mm, the width of the body reaches 1995mm, the wheelbase is 2895mm, and the standard data is moderate. Among the models of the same class, the wheelbase of the Cayenne ranks 87th. Among the models of the same price and class, the trunk volume of the Cayenne ranks 64th. The space is relatively regular, there are no obvious protrusions, and the overall loading capacity is good.

The Porsche Cayenne is equipped with a combination of 4.0 twin-turbo engine (direct injection) and automatic hand (AT). The whole power parameter, the power performance is superior in the same level of engine, which can provide better power performance. The official measured zero-hundred acceleration score of the Cayenne is 3.3S, ranking 50th among SUV models above 800,000.

Cayenne’s active/passive safety configuration is comprehensive, includingAutomatic parking,Zero tire pressure endurance tires,Automatic parking,Steep slope,uphill assist,Knee airbag,HUD head-up display,Anti-lock braking (ABS),Brake force distribution (EBD/CBC, etc.),Brake assist (EBA/BAS, etc.),Traction control (ASR/TCS, etc.),Active Noise Cancellation,Engine start stop,Side safety air curtain,Mobile phone wireless charging,Night vision system,LED daytime running lights,Front reversing radar,Tire pressure monitoring,Steering wheel heating,Body stability control (ESP/DSC, etc.),Rear reversing radar,Fatigue reminder,Remote parking,Child seat interface,Lane Keeping (LKAS)Wait for the configuration.

Of which,Automatic parkingIt can avoid stepping on the brakes for a long time or needing to pull frequently.Steep slopeIt can safely pass through steep slopes at low speeds.Knee airbagReduce the damage to the occupant’s knee in the vehicle interior during the second collision.

If the above data, participation, etc. do not provide a comprehensive understanding of Cayenne, then we can give you a more comprehensive reference based on the word-of-mouth information of users who have purchased Cayenne in history. You can see that what you are most satisfied with about Cayenne is that its navigation is very easy to use. In addition, the appearance is too handsome and the space is enough.

Huizhou Xingtu Lanyue price reduction news, the lowest price 175,900! only this time

At Autohome Huizhou Promotion Channel, we bring you exciting news that an attractive promotion is underway. As a high-profile model, Xingtu Lanyue has launched a cash discount of up to 18,000 yuan in the Huizhou market, allowing car buyers to experience the charm of this luxury SUV at a more affordable price. The minimum starting price has been reduced to 175,900 yuan, which is not to be missed. Friends who want to seize this wave of car buying opportunities, don’t hesitate to click "Check Car Price" in the quotation form and let us help you get better car buying discounts.

惠州星途揽月降价消息，最低售价17.59万！仅此一次

The exterior design of Xingtu Lanyue shows a minimalist and elegant modernist style. In the front face, an atmospheric and delicate hexagonal air intake grille is used, with smooth lines, which complement the sharp headlights, giving the vehicle a strong visual impact. The streamlined design on the side of the body highlights power and movement, and the overall lines are tough, giving a sense of stability of a luxury SUV. The tail design pays attention to details, and the taillights are unique in shape, echoing the front of the car, creating a perfect fusion of technology and fashion. Xingtu Lanyue’s exterior shape not only meets functional needs, but also reflects the brand’s persistent pursuit of design aesthetics.

With its exquisite side design, Xingtu Lanyue shows the perfect blend of elegance and power. The body measures 4970mm x 1940mm x 1792mm, with a wheelbase of 2900mm, ensuring a spacious interior and excellent driving stability. Its front and rear track are both 1644mm, reflecting fine engineering design. The tire specification is 245/50 R20, which shows high performance and sporty sense both visually and performance. With the delicate wheel design, it jointly shapes its unique side profile.

惠州星途揽月降价消息，最低售价17.59万！仅此一次

The interior design of Xingtu Lanyue shows the perfect fusion of luxury and technology. The steering wheel is wrapped in exquisite leather to provide a comfortable grip, and supports manual up and down + front and rear adjustment to ensure the best operating position for the driver. The highlight of the central control area is the large 15.6-inch screen, which integrates multimedia system, navigation, telephone and air conditioning control, bringing users an intelligent driving experience. In terms of seats, the seat material is made of high-grade leather. The main and passenger seats are equipped with front and rear adjustment, backrest adjustment and high and low adjustment functions. The driver’s seat is also equipped with a power seat memory function to ensure the comfort of long-distance driving. The front seat is equipped with heating and ventilation functions, while the second row of seats also supports front and rear adjustment and backrest adjustment, resulting in a flexible spatial layout. The rear seats can be reclined in proportion, providing multiple possibilities for loading or passenger travel.

惠州星途揽月降价消息，最低售价17.59万！仅此一次

Xingtu Lanyue is equipped with a powerful 2.0T turbocharged engine with a maximum power of 192 kilowatts and a power output of 261 horsepower. This engine is paired with an 8-speed manual transmission to ensure a smooth driving experience and high-efficiency performance, meeting the driver’s demand for power and handling.

Summarizing the owner’s point of view, Xingtu Lanyue has won his favor with its international exterior design, and the stable and atmospheric body lines just fit his aesthetic. As he said, the charm of the appearance largely depends on personal preference, and Lanyue obviously meets his expectations for large-size models visually. Therefore, whether in daily driving or in the praise of friends, Xingtu Lanyue has become a masterpiece in the hearts of car owners.

The 2024 Medici Innovative Drug Industry Ecological Cooperation Conference was a complete success

On March 18, the Medici Innovative Pharmaceutical Industry Ecological Cooperation Conference with the theme of "20 Years of Beauty, Creating the Future Together" was successfully held in Shanghai Zhangjiang Science Hall. After 20 years of hard work, Medici (688202) has taken empowering biomedical innovation research and development as its mission, grown side by side with China’s biomedical industry, and has developed into a leading one-stop biomedical pre-clinical R & D service platform in China.

At the conference, more than 500 industry leaders from various fields such as government, industry, academia, and finance gathered to participate in the grand event. Together, they reviewed Medisi’s outstanding history over the past 20 years, witnessed the launch of its globalization prelude, and the grand launch of two key technology service platforms. In addition, the conference also held a number of thematic dialogues around current hot topics. The guests brainstormed and discussed in depth the future development direction of the innovative drug industry ecology. They offered suggestions for the sustainable development of the industry, pointed out the way forward, and worked together to explore new opportunities for the cooperative development of Chinese pharmaceutical companies.

Twenty Years of Prosperity　Starting from "New" with high hopes

First of all, Mr. Wu Qiang, member of the Standing Committee of the Shanghai Pudong New Area District Committee and deputy head of the district, delivered a warm opening speech, expressing his heartfelt congratulations on Medici’s brilliant achievements over the past 20 years. He deeply reviewed how Medici participated in and witnessed the rapid development of the biomedical industry in Pudong, established an academician innovation drug ripening center, was approved by large enterprises to open an innovation center, and made outstanding contributions to the construction of the new drug empower ecosystem, and eagerly looked forward to Medici’s ability to continue to expand the breadth and depth of the industry and promote the vigorous development of the biomedical industry more widely. Finally, Vice Mayor Wu Qiang said that Pudong New Area will unswervingly promote institutional reform, provide a broader development space and more powerful policy support for the biomedical industry, and call on entrepreneurs and investors to come to Pudong to join hands in creating a new future of technological innovation!

Song Ruilin, executive chairperson of the China Pharmaceutical Innovation Promotion Association, pointed out in his speech that in the context of the reshaping of the global economic structure and the increasingly complex geopolitical situation, China’s biomedical industry is standing at a critical crossroads, facing both unprecedented challenges and huge development opportunities. In recent years, with the successive introduction of a series of policy plans, China’s biomedical industry has ushered in an unprecedented spring breeze of development, while Medicis and others will usher in a more rapid development momentum and contribute more to the rise of the biomedical industry. Finally, President Song Ruilin confidently emphasized that 2024 will be a year of hope for the biomedical industry.

Chen Chunlin, founder and CEO of Medici, expressed his sincere gratitude to all the guests in his speech. He mentioned that Medici has been fortunate to witness the rise of China’s biomedical industry and has achieved outstanding results in scientific research innovation, industrial integration and business expansion. He stressed that the current biomedical industry is ushering in a new spring, full of unlimited opportunities. As an important part of new drug research and development, Medici shoulders the important task of promoting the implementation of source innovation and empowering the development of the industry. Dr. Chen said that Medici looks forward to working with more partners to jointly build an ecological empowering circle and promote the sustainable innovation and development of the biomedical industry.

Chen Kaixian, an academician of the Chinese Academy of Sciences, delivered a wonderful keynote report, entitled "Biomedical R & D Innovation and Industrial Development", which deeply analyzed the opportunities and challenges of biomedical innovation and development, and comprehensively sorted out the situation, progress and problems of biomedical development in our country. He elaborated on the four major development trends of global pharmaceutical innovation, and keenly pointed out the shortcomings and bottlenecks in the field of biomedical development in our country. At the same time, Academician Chen also shared the hot spots of scientific and technological innovation, especially the application of artificial intelligence in the field of new drug research and development, which brought dawn to the research and development of new drugs. Finally, we look forward to strengthening cooperation from all walks of life and contributing to Shanghai’s goal of building a source of biomedical technology innovation and a world-class biomedical industry cluster.

The prelude to globalization has begun, deeply empowering the transformation of innovation achievements

Next, the prelude to a new chapter of globalization was officially opened, and the Transformation Ceremony of Medici’s Biomedical Source Innovation Achievements opened. This landmark moment not only fully demonstrates Medici’s outstanding innovation achievements in the field of biomedicine, but also indicates that these achievements will be quickly transformed into strong actual productivity, injecting new vitality and momentum into global cooperation and development, and enabling the drug research and development industry chain to innovate at the source and extend globally!

At the ceremony, Pharma representative Zhang Lianshan, research institute representative Li Bin, CXO industry representative Chen Chunlin, Zeng Dewan, Rong Yiping, AI intelligent medicine representative Zhang Long, overseas Biotech representative Mr. Sam Waksal, domestic Biotech representative Cheng Changfu, Liu Binlei, investor representative Zhao Yongsheng came to the stage one after another to join hands to start the transformation of biomedical source innovation achievements. Medici will take this launch ceremony as an opportunity to further strengthen communication and cooperation with domestic and foreign partners, jointly explore new paths for the transformation of biomedical innovation achievements, and work together to promote the sustainable prosperity and development of the global biomedical industry, and jointly create a better future.

Next, Mr. Sam Waksal shared his views on the original innovation of the biopharmaceutical industry and the globalization of innovative drugs, saying that under the leadership of Dr. Chen, Medici has developed over the past two decades and has become a leader in the industry, and its achievements are remarkable. Although the biomedical industry is young, it has shown great potential and influence on a global scale, driving sustained economic growth. Today, the pharmaceutical and biotechnology fields are closely linked, and they are jointly committed to the research and development of innovative drugs. Medici has played a pivotal role in it, not only transcending national borders and politics, but also injecting new vitality into the global economy. Finally, we look forward to the future to continue to witness their greater contributions to human health and economic development.

Innovative drug going overseas strategy and successful case sharing

Innovative drugs continue to go overseas, how to seize the global market? Under the chairpersonship of Qiangjing, founder & chairperson of Xinnuowei and founding partner of Xingze Capital, Zhang Lianshan, deputy general manager and president of global R & D of Hengrui Pharmaceutical, Xue Tongtong, founder, chairperson and CEO of Yilian Bio, Peng Jianbiao, president of Jimin Trustworthy Small Molecular Innovation Research Institute, Pan Wensen, partner of the Hong Kong office of Gaowin International Law Firm, and Lin Qingcong, executive vice president and president of the US company of Medici, industry leaders gathered together to discuss the strategy and path of innovative drugs going overseas.

Zhang Lianshan, Xue Tongtong, and Peng Jianbiao shared their respective strategic plans and successful experiences in innovative drugs going overseas from the perspective of pharmaceutical companies. They elaborated on how to achieve global distribution of innovative drugs through precise positioning, technological innovation, and international cooperation, providing useful inspiration for pharmaceutical companies.

From the legal perspective, Penvenson deeply analyzed the legal challenges and coping strategies faced by innovative drugs going overseas. He emphasized the importance of compliance and provided practical legal advice to the participants.

As an investor and a representative of pharmaceutical companies, Qiangjing shared Xinnovi’s unique experience in innovative drug research and development and internationalization, and said that Xingze Capital has been paying attention to the research and development and industrialization of innovative drugs, providing funds and resources for potential enterprises and projects, and promoting the globalization process of China’s innovative drugs.

Lin Qingcong shared the rich experience and profound lessons of Medici in assisting pharmaceutical companies to enter the international market from the perspective of CRO. He emphasized that Medici’s one-stop biomedical pre-clinical R & D service platform can support the whole process of drug discovery from target discovery to IND declaration. In addition, the new drug empower ecosystem of the Academician Innovative Drug Ripeness Center can help new drug funding, transactions and other issues. At present, Medici has established a research and development base in Boston, which will further empower the drug to go overseas and achieve higher value.

Multi-site blockbuster unveiling　Two key technology platforms released

At this grand ceremony, Medici’s two major science and technology platforms made a major appearance, attracting extensive attention from the participants.

1. Drug Discovery & Pharmaceutical Research Science Key Technology Platform

Jian Liu, President of Medici’s Drug Discovery and Pharmacy Research Division, introduced the Drug Discovery & Pharmacy Research Science Key Technology Platform. The platform includes a new drug platform for targeted protein degradation, a small nucleic acid drug development platform, an ADC drug development platform, a polypeptide macrocyclic peptide drug development platform, an AI drug development platform, a synthetic biology platform, a green chemistry platform, a drug metabolite platform, etc., to support the innovation of various drug forms. It is worth noting that Medici has a complete R & D platform for small molecule innovative drugs; an AI drug discovery platform empowers and accelerates new drug development from target discovery to the generation of preclinical compounds; a green chemistry platform and a synthetic biology platform enable the synthesis of various complex compounds.

2. Key technology platform for preclinical research science

Subsequently, Zhang Haizhou, president of Medici’s preclinical research division, elaborated on Medici’s key technology platform for preclinical research science. In terms of discovery biology, Medici has built in vitro screening platforms, such as PROTAC, small nucleic acids, ADC, etc., as well as cutting-edge technologies such as synthetic biology and nano-antibody discovery. In terms of pharmacological efficacy, there are advanced platforms such as in vivo imaging, small animal surgical excision, and in vitro imaging. In addition, Zhang Haizhou focused on introducing DMPK and safety service platforms for various advanced drug types such as PROTAC, oligonucleotide, ADC, mRNA, and cellular immunity, as well as pre-clinical service platforms such as inhalation medication, ophthalmic medication, and topical medication.

The release of the two key technology service platforms not only fully demonstrates the outstanding strength and profound heritage of Medici in the field of biomedical pre-clinical research and development, but also provides a solid and powerful support for its future customers to better empower.

Industry leaders gather together　A new blueprint for biomedicine

Frontier technologies and industrial applications of drug discovery

How to promote the transformation of basic scientific research results in China? What are the future development trends? Ma Dawei, academician of Chinese Academy of Sciences and researcher of Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, Tao Weikang, vice president and general manager of global innovative drug research and development of Qilu Pharmaceutical Group, Liu Dongzhou, general manager of CSO/Innovative Drug Global R & D Center of East China Pharmaceutical, Shen Hong, head and senior vice president of Roche China Innovation Center, and Xu Yaochang, chairperson and CEO of Yuyu Pharmaceutical, shared their insights from their respective fields. Liu Jian, president of Medici Drug Discovery & Pharmaceutical Research Division, moderated this keynote dialogue.

Faced with the difficulty of transforming basic research, Ma Dawei shared in depth the course of cooperation with Academician Medisi’s Innovative Pharmaceutical Refinement Center, believing that this cooperation has achieved remarkable results in the transformation of scientific and technological achievements, bringing a mutually beneficial and win-win situation to both parties. At the same time, Shen Hong, head of Roche China Innovation Center and senior vice president, also introduced the Roche Accelerator, the world’s first self-established and operated accelerator project. The project fully integrates Roche’s own resources and advantages, and provides start-ups with all-round support including funding channels, cooperation opportunities, R & D experience, and advanced experimental equipment in an agile and flexible way to help start-ups grow rapidly and promote the development and industrialization of innovative drugs.

Tao Weikang, Liu Dongzhou, Shen Hong, Xu Yaochang and other pharmaceutical company leaders, based on the practical experience of their respective companies, discussed in depth how to accurately grasp their own advantages and differentiate the layout of innovative drug industry pipelines. They stressed that each company should formulate R & D strategies according to its core competitiveness. Facing the ever-changing technological challenges and changing future development trends, they said that pharmaceutical companies need to maintain keen insight and keep up with the pace of industry development. In sharing, they not only showcased the fruitful results achieved by their respective companies in the field of innovative drugs, but also provided valuable experience and inspiration for the future development of China’s innovative drug industry.

Transformation of new technologies for preclinical research of innovative drugs

Under the chairpersonship of Peng Shuangqing, Chief Scientific Officer of Medici, an in-depth discussion on the transformation of new technologies in preclinical research of innovative drugs was launched. The conference focused on breaking through the model barriers in preclinical research, technology development trends, market demand and future challenges, achievement transformation, and multi-party linkage.

Xu Zengjun, the former chief scientist of the Drug Evaluation Center of the State Food and Drug Administration and the founder of AstraZeneca Medicine, deeply analyzed the multiple challenges of preclinical research, such as the lack of understanding of the principle, mechanism and predictive correlation between models and diseases, as well as drug regulatory issues. Xia Mingde, founder/chairperson/CEO of Innolake Pharmaceutical, deeply analyzed the key role of translational medicine in crossing the "valley of death" in new drug development, and also pointed out the key role of translational medicine in crossing the "valley of death". Dr. Wang Yaning, former director of the clinical pharmacology department of the US FDA and CEO of Langlai Technology, pointed out that the FDA is cautious about preclinical data. Although AI technology is applied, there is insufficient data. It is necessary to optimize methods, strengthen translational research and data cooperation to improve R & D efficiency. Wang Haisheng, founder/chairperson/CEO of Sihe Genomics, emphasized the importance of AI in understanding the structure of genes and RNA, and mentioned the challenge of genetic differences between animal models and humans and the attempt of new organoid technologies. Yang Xiaobao, founder/chairperson/CEO of Bioscience, shared his research and development experience in the field of protein degradation, emphasized the importance of safety evaluation in preclinical research, and mentioned that with the help of Medici’s one-stop preclinical service platform, they successfully obtained clinical approval in China and the United States. Finally, he emphasized the enlightenment of tracking the layout of large companies such as MNC for Biotech.

Following the glorious past, we will move towards a glorious tomorrow. This 20th anniversary celebration of Medici is not only a feast for a full house, but also a brainstorming that concerns the development of the next 20 years. In the past two decades, Medici has not only witnessed the magnificent development history of the industry, but also acted as a vanguard force driving the continuous upgrading of the industry. In the future, Medici will adhere to innovation, deepen the field of biomedical pre-clinical research and development, lead technological innovation, enrich the matrix of R & D service platforms, layout the global market, ride the wind and waves, and move forward in the next two decades! (CIS)

Proofreading: Wang Jincheng